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Fig. 6. Xdsh is required in ventral/lateral and dorsal tissues for blastopore closure. Plot of blastopore closure in embryos expressing Xdd1 in ventral, dorsal, or all four blastomeres (circumferential) at the four-cell stage (***P<0.001, n=36 control, 30 each dorsal and ventral, 21 circumferential). Note the morphology of the blastoporal boundary in each condition; the affected side is visibly less taut in each case (red arrowheads).