Fig. 2. Sexual dimorphic expression pattern of Lim1 in the developing reproductive tract. Lim1^tlz expression in the developing urogenital system in females (A,C,E,G,I) and males (B,D,F,H,J). (A,B) Ventral view at E14.5. Note that Lim1^tlz expression in the Müllerian duct is thinner in males compared to its expression in females. (C,D) Ventral view at E15.25. Lim1^tlz expression in the Müllerian duct is discontinuous in the anterior region of males (open arrow in D). (E,F) Ventral view at E15.5. Lim1^tlz expression in the Müllerian duct is fragmented in males (arrow in F). (G,H) Ventral view at E16.5. Lim1^tlz expression in the Müllerian duct is restricted to a few vesicles in males (arrow in H). (I,J) Lateral view at E17.5. Lim1^tlz is expressed in the presumptive oviduct, but not in the uterus in females (I). The open arrowhead indicates the boundary of the presumptive oviduct and uterus. Lim1^tlz expression is upregulated in the male reproductive tract (J). a, adrenal; e, epididymis; k, kidney (metanephros); md, Müllerian duct; od, oviduct; ut, uterus; v, vas deferens; wd, Wolffian duct. Scale bar: 500 µm.