Fig. 2. Wee1 is required for Xenopus gastrulation. (A) Embryos injected with MO-Control, MO-Wee1 or MO-Wee1+WT Wee1 RNA were examined for blastopore formation at stage 10.5 and 11. MO-Wee1 disrupts blastopore formation, which is rescued by WT-Wee1 RNA. (B) Percentage of embryos with gastrulation defects: MO-control (n=64), MO-Wee1 (n=243) and MO-Wee1+WT RNA (n=47).