Fig. 4. Genetic Moesin loss-of-function disrupts rhabdomere morphogenesis. Confocal micrographs show F-actin staining (red) and Moesin immunolocalization (green). (A) Photoreceptors lacking Moesin exhibit extreme F-actin disorganization at the apical surface (arrowheads) in homozygous null Moe^PL54 65% pd eye clones. (B) Photoreceptors are missing (asterisks) in 65% pd eye clones of a second allele, Moe^X5. (C,D) Retinas of 1-day post-eclosion Moe^G0323/Moe^G0323; Rho1^72R/CyO flies show wild-type Moesin immunolocalization at the rhabdomere base in cross-section (C) and side view (D, arrowheads). In side view, Moesin is prominent on the apical surfaces of cone cells lying above the rhabdomeres. Scale bars: 10 µm.