Fig. 6. Follicle cell DNA endoreplication, but not gene amplification, is perturbed by mutations in dm. (A) An overlay of DAPI/hGFP images shows a clone of homozygous dm²/dm² mutant cells outlined in white. (B) An overlay of hGFP/anti-BrdU images of the same field of follicle cells shows that a much smaller proportion of dm² mutant follicle cells than wild-type cells incorporate BrdU. (C) An overlay of DAPI/hGFP images shows a large clone of dm²/dm² mutant cells, present in a stage 11 egg chamber, outlined in white. (D) In the overlay of DAPI/BrdU images of the same mutant clone, gene amplification can be detected by the presence of puncta of BrdU incorporation in both the heterozygous and dm² mutant cells.