Fig. 6. Normal specification of neural crest progenitor cells in
mobm610 embryos. (A,B) In situ hybridization analysis of
snail2 (A) and foxd3 (B) expression. The patterns are
indistinguishable between wild-type and mobm610 embryos at
10-somite stage. (C,D) sox10 expression at 10- (C) and 20- (D) somite
stages is also indistinguishable between wild-type and
mobm610 embryos (A-D; wild-type controls not shown). (E,H)
crestin expression in wild-type (E,G) and mobm610
embryos (F,H) at 10- (E,F) and 20-somite stages (G,H). Expression of
crestin is completely absent in the head (asterisk) of
mobm610 embryos and reduced in the trunk. All panels show
dorsal views of flat-mount preparations, anterior to the left. The eye (e) and
otic vesicle (ov) are marked for orientation.