Fig. 2. Tyr, Tyrp1 and Dct expression in the cilary margin is expanded in the Chx10^or-J/or-J E13.5 NR. (A) Tyr is expressed in a wild-type E13.5 RPE and ciliary margin (arrow). (B) By contrast, in the Chx10^or-J/or-J E13.5 ciliary margin, the Tyr expression domain is expanded (arrow). (C) Tyrp1 is expressed in the wild-type RPE and ciliary margin (arrow). (D) Tyrp1 expression in the Chx10^or-J/or-J ciliary margin is expanded (arrow). (E) A wild-type section showing expression of Dct in the RPE and ciliary margin (arrow). (F) In the Chx10^or-J/or-J ciliary margin, the Dct expression domain is enlarged (arrow). Scale bars: 40 µm in A; 32 µm in B,C,E; 25 µm in D,F.