(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 4. Context-dependent relationships between signaling pathways and the retinal determination gene network (RDGN). Positive interactions are shown in green, negative interactions in red. Arrows represent activation or induction; blunt-end lines represent transcriptional and/or post-translational repression. DAC, DACHSHUND; DPP, Decapentaplegic; EGFR, Epidermal growth factor receptor; EYA, Eyes absent; HH, Hedgehog; SHH, Sonic hedgehog; SO, Sine oculis; WG, Wingless.