Fig. 2. Adult eye phenotypes resulting from altering RD gene expression.
Photographs of adult eyes, except for E, F and J, which were dissected from
unhatched pupae. For clarity, the boundary of eye tissue is outlined in the
GMR-Gal4 UAS-AML1-ETO and lz-Gal4 UAS-AML1-ETO flies. Two
different driver lines (lz-Gal4, B-F; GMR-Gal4, H-K) were
used to express ectopically different fly and mammalian RD proteins. The eye
color differences are due to the presence or absence of white (or a
mini-white transgene), which is necessary for eye pigmentation. The
relevant genotypes of the flies are as follows: (A) wild type; (B)
lz-Gal4; UAS-lz; (C) lz-Gal4; UAS-run; (D)
lz-Gal4; UAS-AML1; (E) lz-Gal4; UAS-AML1-ETO; (F)
lz-Gal4; UAS-lz-enR; (G) lznull; (H)
GMR-Gal4; UAS-lz; (I) GMR-Gal4; UAS-run;
(J) GMR-Gal4; UAS-AML1; (K) GMR-Gal4
UAS-AML1-ETO.