Fig. 3. Altered cardiac transcriptional program in
Tbx20lacZ/lacZ embryos. (A-H) Whole-mount in-situ
hybridization analysis of E8.25-9.5 wild-type or
Tbx20lacZ/lacZ embryos showing expression of genes
indicated. Arrows in B indicate cranial limit of Tbx5 expression.
Arrows in E indicate cells of the primary heart field. (I)
Tbx20lacZ/+ and Tbx20lacZ/lacZ embryos
bearing the Mef2c-AHF-hPLAP transgene, stained for alkaline
phosphatase activity. oft, outflow tract; wt, wild type.