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Fig. 8 Genetic interactions of Ssdp1 with Lim1 and Ldb1. (A-D) E9.5 embryos obtained by crossing Ssdp1+/hsk and Lim1+/- mice. (A) Wild-type embryo. (B-D) Double heterozygotes, which can be classified into three types: I, normal (B, n=6); II, microcephaly (C, n=5); III, dwarfism (D, n=4). (E-G) E9.5 embryos obtained by crossing Ssdp1+/hsk and Ldb1+/- mice. (E) Wild-type embryo. (F,G) Double heterozygotes showing no apparent abnormalities (F, n=7) or varying degrees of abnormality (G, n=6). Scale bar: 400 µm.