Fig. 3. Stereologic analysis of the adult hippocampus. (A) Prox1 antibody staining of the dentate showing that the overall organization of the dentate is intact in frizzled 9 mutants. (B) Heterozygous and null frizzled 9 mutants have small but statistically significant decreases in the number of dentate granule cells but normal numbers of pyramidal neurons. For each genotype six animals (three male and three female) were used for counting.