Fig. 6. Seizure latency is decreased in frizzled 9 mutants. (A) Time in seconds to first twitch and to tonic-clonic seizure are shown. The latency of +/– and –/– mice is about half for each endpoint. n=6 for each genotype with 3 females and 3 males of each genotype. ^*P<0.05. (B) GFAP immunostaining in adult frizzled 9 +/+, +/– and –/– mice. (C) Calbindin immunostaining in adult frizzled 9 +/+, +/– and –/– mice.