Fig. 8. Fasciculation is disorganized in blue kite (bluk) and
coming apart (coma), blue kite (bluk),
clewless (clew) and blind date (blin)
mutants. (A-F) Surface-rendered 3D reconstructions of confocal images taken
from 6 dpf live Brn3c:mGFP larvae. Dorsal views (A,C,E,G,I) and
mirror-image ventral views (B,D,F,H,J) of the same tecta are shown. On the
dorsal surface, axon fascicles are visible within the tectal neuropil of wild
type (A) (arrowheads). The ventral view (B) demonstrates the characteristic
dense grid of arbors. (C,D) In coma, fascicles both in the optic
tract (hatched rectangle in D) and in the neuropil are disorganized. (E-J) In
bluk, clew and blin, fascicles within the neuropil are
greatly reduced (E-I) and axon termations appear diffuse. Asterisks indicate
melanophores in the skin. Scale bars: 20 µm.