Fig. 4. Hdac1, p27 and
N-Tcf3 suppress add- or Wnt-mediated retinal
proliferation. Left bars (red, blue) indicate the ratio of the number of
BrdU-positive cell clusters to total number of cell clusters in add
mutant retinal cells expressing EGFP (n=39), Hdac1 (n=58),
p27 (n=43) and
N-Tcf3 (n=148). Right bars (grey)
indicate the ratio of the number of BrdU-positive cell clusters to total
number of cell clusters in wild-type retinal cells co-expressing
47-ß-catenin and EGFP (n=23), and wild-type retinal cells
co-expressing
47-ß-catenin and Hdac1 (n=48).
*P<0.05 and **P<0.01 versus
control;
2-test.