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Fig. 6. BC migration defects of Drab5S43N and ShiK44A egg chambers. Expression of Drab5S43N, Drab5WT and ShiK44A in egg chambers was driven by slbo-GAL4 at 29°C. To measure the extent of migration, the nurse cell compartment was divided into four equivalent regions (1 to 4: clusters in region 1 have almost completely migrated whereas clusters found in region 4 have not migrated at all; see inset) and the position of the BC relative to this coordinate system monitored. Drab5S43N and ShiK44A led to similar and strong migration defects.