Fig. 5. No evidence for alternate endocrine fate choices in Nkx6 compound
mutants. Immunofluorescence staining for somatostatin (A-D), pancreatic
polypeptide (PP) (E-H) and ghrelin (I-L) in pancreas from wild-type,
Nkx6.2-/-, Nkx6.1-/-, and
Nkx6.1-/-;Nkx6.2-/- embryos at E18.5. Wild type
and Nkx6 compound mutants have similar numbers of
somatostatin+, PP+ and ghrelin+ cells. Scale
bar: 50 µm.