Fig. 2. frk-1 rescues the morphogenetic and differentiation defects of mDf7 homozygous embryos. Embryos homozygous for mDf7 (A) do not express the seam-cell-specific marker recognized by antibody NE2-1B4 (B). Expression of FRK-1 from an extrachromosomal array restores enclosure and elongation (C) and expression of the seam-specific NE2-1B4 antigen (D) to mDf7 embryos. Mouse FerT similarly rescues mDf7 embryos (E,F). A wild-type embryo is shown at the three-fold stage (G) with the NE2-1B4 marker (H).