Fig. 4. Functional difference among the mrp-1 isoforms. The b- and c-type isoforms, but not the e-type isoform, can rescue of the Daf-c phenotype of unc-31(e169);mrp-1(ut153). The means of multiple lines are shown (two lines of b-type, eight lines of c-type, and four lines of e-type). The assays were carried out with 13-128 animals/plate at 25.5°C. Animals carrying an extrachromosomal array of transgenes segregated those that had lost the extrachomosomal array. Dauer formation of these animals was also examined and is shown as a control on the left of each data set.