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Fig. 3. FBF and FOG-1 act downstream of Notch signaling. (A-C) Large arrowheads, oocytes or oocyte-like cells; arrow indicates distal end; vul, vulva. (A) glp-1(gf); fog-1(RNAi); fbf(RNAi) germlines possess small granular oocyte-like cells extending to distal end (arrow). (B) glp-1(gf); fbf(RNAi) germlines are tumorous. (C) glp-1(gf); fog-1(RNAi) germlines are tumorous. Scale bars: 10 µm. (D) Model for FBF and FOG-1 in germline proliferation pathway.