Fig. 4. FBF acts upstream of fog-1 in the sperm/oocyte decision. (A-D)
Broken lines indicate germlines. Green indicates sperm-specific SP56 marker;
red indicates oocyte-specific RME-2 marker. Genotypes, stages and markers are
indicated in micrographs. (A,C) fbf-1 fbf-2 mutants express sperm
marker, but not oocyte marker. (B,D) fog-1; fbf-1 fbf-2 mutants do
not express sperm, but express oocyte marker. Scale bars: 10 µm. (E) Model
for FBF repression of multiple genes in germline sex determination
pathway.