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Fig. 1. Expression patterns of Smad constructs in vivo. (A) Localization of SMA-3 mutant forms. The SMA-3 AMA protein accumulates in the nucleus, similar to the accumulation of wild-type SMA-3. The other dominant-negative SMA-3 mutants have a similar localization pattern (data not shown). (B) The expression pattern of a sma-2::gfp transcriptional fusion gene in (B1) the whole animal, (B2) pharynx, (B3) intestine and (B4) hypodermis. (C) A functional genomic clone of sma-2 excluding the two large introns.