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Fig. 3. The SMA-3 C-terminal mutants activate a negative-feedback loop. All of the sma-3 constructs were co-injected with sma-3::gfpC. (A) The fluorescence of sma-3::gfpC alone; (B) wild-type sma-3 activates the feedback loop, as does (C) sma-3 {Delta}SMT, (D) sma-3 AMA and (E) sma-3 DME. All photographs were taken under the same conditions with the same exposure time.