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Fig. 4. vps18 is required for pigment formation. (A) Day 2 hi2499A mutants and vps18 are not pigmented. (B-E) The day 5 epithelium of the skin (B,C) and the retina (D,E) is darkly pigmented in wild-type embryos (B,D), whereas vps18 mutants (C,E) have sparse pigment granules (arrows). Scale bar: 5 µm.