Fig. 1. Structure of the pipe locus and location of EMS-generated pipe mutations. (A) Intron structures of the various pipe isoforms are shown. On the far left are the isoform designations of the BDGP (PA-PK) and of Sergeev et al. (Sergeev et al., 2001). Box 10 is pipeST2. All mutations except pipe³ are associated with pipeST2-specific exons. pipe³ is located in the third common exon. (B). Structure of the coding region of PipeST2 showing the location of the eleven EMS-generated mutations. Green vertical bars indicate the position of exon/exon boundaries.