Fig. 6. Grh may prevent apoptosis of thoracic neuroblasts at late stages. (A,B)
Single confocal sections of grhB37 (A) and
grhB37; UAS-P35 (B) MARCM clones, showing that inhibiting
cell-death caspases rescues a large neuroblast at 96 hours. (C) Histogram
showing MARCM clone size for wild type (with elav-GAL4, mean=57.3,
n=61, s.d.=12.7), grhB37 (with elav-GAL4,
n=43, mean=28.6, s.d.=15.7) and grhB37; UAS-P35 (with
elav-GAL4, n=31, mean=32, s.d.=8.6). Although elav-GAL4
driving the UAS-P35 transgene rescues the neuroblast in
grhB37 clones at 96 hours, it does not significantly
increase clone size. (D) Histogram showing the percentage of MARCM clones
containing a large neuroblast at 96 hours (sample sizes and genotypes are as
in C). elav-GAL4 driving the UAS-p35 transgene rescues the
presence of a large neuroblast in >40% grhB37
clones.