Fig. 6. Nephrogenic progenitors are preferentially lost in T-Cre;
Fgf8Flox/
2,3 kidneys. (A,B,E,F)
E14.5 kidneys; (C,D,G,H) E16.5 kidneys. (A-D) Sustained expression of the
stromal marker Foxd1/BF2 in sections from whole-mount ISH of control
(A,C) and T-Cre; Fgf8Flox/
2,3
(B,D) metanephroi. (E-H) Depletion of the cap cell marker Cited1 demonstrated
by immunohistochemistry of control (E,G; arrowheads indicate cap formation)
and T-Cre; Fgf8Flox /
2,3 (F,H)
metanephroi.