Fig. 7. Substantial loss of multiple metanephric markers occurs in T-Cre; Fgf8^Flox/2,3 kidneys between E14.5 and E16.5. Expression patterns for tissue-specific markers of metanephric differentiation in control and mutant E14.5 and E16.5 metanephroi by thin-section ISH. Arrowheads in the Wt1 panels indicate podocyte expression domains; arrows in the Pax2 panels indicate renal vesicles. Scale bar: 20 µm.