Fig. 3. Effect of ADAM17 deficiency on prenatal mammary development. (A) Carmine-stained E18.5 mammary gland/skin whole mounts. Scale bar: 500 µm. (B) Average number of branches in the thoracic (2 and 3) mammary glands of Adam17^–/– embryos and neonates (white circles), Egfr^–/– neonates (white squares) and their respective wild-type littermates (black symbols). (C) Overall lengths of the thoracic mammary ductal trees of Adam17^–/– embryos and neonates, Egfr^–/– neonates and their wild-type littermates.