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Fig. 4. RNF17 granules are distinct organelles in the testis. Double immunostaining of adult testis sections was performed with antiserum 1774 (red) and anti-TDRD1 antibodies (green) or anti-LAMP2 antibodies (green). RNF17 granules (red) are prominent in spermatocytes (A,C) and elongating spermatids (B,D). Dynamic changes of chromatoid bodies (green) are seen in spermatocytes (A) and spermatids (B). Lysosomes (green) are not present in spermatocytes (C) but are abundant in spermatids (D). Scale bar: 10 µm.