Fig. 2. Disorganization and loss of planar cell polarity in Dll1^hyp/-Jag2^-/- cochleae. Scanning electron microscopy of the basal region of cochleae of the indicated genotypes. (A,C,E) Low-power views. (B,D,F) Higher power views of the outer hair cell rows. Note the extremely disorganized and disoriented state of the hair cell bundles in the Dll1^hyp/-Jag2^-/- cochleae (F). In addition, some of the hair cells appear immature (arrow), with stereocilia covering the entire apical surface and not displaying the graded heights they would normally have acquired by this time. Some of this disorientation is also apparent in Jag2^-/- cochleae (D), where some of the stereocila bundles on the outer hair cells do not orient properly (arrows). Scale bar: 50 µm in A,C,E; 10 µm in B,D,F.