(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 8. Ptch1 expression in wild type and Sufu-/- mutants. Whole-mount in situ hybridization using a Ptch1 digoxigenin-labeled riboprobe on wild-type (A) and Sufu-/- (B) embryos at 9.5 dpc. The Sufu-/- embryo exhibited an expansion of the expression domain and gross overexpression of Ptch1.