Development -- de Melo et al. 132 (2): 311 Figure IG9

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Fig. 9. Model for the generation of RGCs through a Dlx1/Dlx2 dependent pathway (A). Dlx1/Dlx2-expressing cells downregulate Chx10. These cells may then establish Brn3b expression and terminally differentiate into RGCs. The majority of RGCs are derived from Math5/Brn3b co-expressing populations of retinal progenitors (B). We suggest that Dlx1/Dlx2-specified RGCs might represent a distinct late-born RGC population in the murine retina.