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Fig. 5. Shh expression in megalinlox/lox and megalinlox/lox/Meox2tm1(cre)Sor E10.5 embryos. (A,C) Lateral and (B,D) frontal head aspects of whole-mount in-situ hybridization for Shh in E10.5 embryos, indicating expression in the AEP of megalinlox/lox (A,B; arrowheads) but not megalinlox/lox/Meox2tm1(cre)Sor embryos (C,D, arrowheads). bpd, basal plate of the diencephalon; Zli, zona limitans intrathalamica.