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Fig. 6. C/EBP{delta} induces involution-related genes in HC11 cells and cooperates with p53 in inducing apoptosis. The non-transformed mouse mammary epithelial cell line HC11 was transiently transfected with constructs expressing the indicated proteins, and harvested after 2 days. (A) Northern analysis of the indicated genes in total RNA from representative samples are shown. (B) The flow cytometric quantification of arrested (G1 DNA content) and (C) apoptotic cells (sub-G1 DNA content) represents the means ± s.d. of six to eight samples from three to four independent experiments.