Fig. 3. Reelin inhibits the migration of GN11 cells in Boyden's chamber assay. (A) In a chemotactic assay, reelin-CM did not alter the migration of GN11 cells compared to control-CM. However, the haptotactic response of these cells was significantly inhibited by the presence of reelin-CM (***P<0.001; Student's t-test). On average, 469.1±49.76 cells/mm² migrated in the presence of control-CM while 183.5±30.90 cells/mm² migrated in the presence of reelin-CM. Means ± s.e.m. obtained from 12 independent experiments.