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Fig. 1. An smc1 null mutation increases expression of the ctK allele of cut. (Lower left) A ctK wing with margin nicks. (Lower right) Schematic of the cohesin complex. (Upper left) The distribution of wing nicks in ctK males heterozygous for the viable P insertion used to generate smc1exc46 (blue), and in ctK males heterozygous for smc1exc46 (red). The curved lines show normal distributions calculated from the histograms. (Upper right) Box plots of the wing nick distribution for both genotypes; horizontal lines for each box represent the tenth, twenty-fifth, fiftieth, seventy-fifth and ninetieth percentiles. The difference between the two distributions is significant using the Bonferroni/Dunn test (P<0.0001). The smc1exc46 mutation gives fewer nicks, indicating greater cut expression.