Fig. 1. An smc1 null mutation increases expression of the
ctK allele of cut. (Lower left) A
ctK wing with margin nicks. (Lower right) Schematic of the
cohesin complex. (Upper left) The distribution of wing nicks in
ctK males heterozygous for the viable P insertion used to
generate smc1exc46 (blue), and in ctK
males heterozygous for smc1exc46 (red). The curved lines
show normal distributions calculated from the histograms. (Upper right) Box
plots of the wing nick distribution for both genotypes; horizontal lines for
each box represent the tenth, twenty-fifth, fiftieth, seventy-fifth and
ninetieth percentiles. The difference between the two distributions is
significant using the Bonferroni/Dunn test (P<0.0001). The
smc1exc46 mutation gives fewer nicks, indicating greater
cut expression.