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Fig. 8. Increased apoptosis in the hindlimbs of Fgfr1Co/Co;Hoxb6-Cre mice detected by staining with LysoTracker Red. Whole-mount images of E10.5 (A,B), E11.5 (C,D) and E12.5 (E,F) limbs. Arrows and arrowheads in mutant limbs indicate apoptotic cells. The arrowhead marked with an asterisk in F indicates an apoptotic area that is out of focus, but it was confirmed under the microscope. Wt, wild type; Mt, mutant.