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Fig. 2. Expression of MAD1 and SMAD4130S generates phenotypes that resemble Mad loss-of-function phenotypes. (A) Wild-type wing. (B) UAS.Mad/ptc.Gal4 with extra vein tissue between L3/L4/L5. (C) UAS.Mad12/69B.Gal4 appears wild type. (D) Mad11/Mad12 with no L2, abnormal L4/L5, no crossveins and a large margin notch (not to scale). (E) UAS.Mad1/69B.Gal4 with truncated L2/L3/L4/L5, abnormal crossveins and a moderate margin notch. (F) UAS.SMAD4130S/A9.Gal4 with truncated L2/L3/L4/L5 and a small margin notch.