Fig. 9. Implantation of Fgf4 protein-soaked beads into fgf10/dae fin buds. Dorsal (A-C) and lateral (A'-C'') views of 2.5-day-old embryos, anterior towards the left. Expression of genes indicated was examined by in situ hybridisation in operated left-hand side (A'-C') and unoperated right hand side fin buds (A''-C''). Fgf4 protein is unable to rescue expression of fgf8 (A-A''). Conversely, Fgf4 protein is able to rescue the expression of both shh (B-B'') and eng1a (C-C'') in operated fin buds. Yellow asterisks indicate the position of implanted beads (A'-C'). LV, left view of embryo; RV, right view of same embryo.