Development -- Wang et al. 132 (22): 5103 Figure IG6

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 6. Ectopic Hh pathway activation restores cell cycle gene expression and bipolar cell development in retinal explants from ${alpha}$ -Cre;Shh^–/c mice. Retinal explants from wild-type and ${alpha}$ -Cre;Shh^–/c mice at P1 were cultured for 2 (A-L) or 9 (M-X) days and processed for in situ hybridization to detect mRNA for Gli (A-D), cyclin D1 (E-H) and Chx10 (I-L) or stained for Hoechst to reveal nuclei and anti-PKC (M-P), anti-CRALBP (Q-T) and anti-syntaxin (U-X) antibodies. The peripheral region of the explants is shown in these panels. Scale bar: 100 µm.