Fig. 2. DIC micrographs of itr-1 and unc-43 gain-of-function female gonads. (A) In unmated fog-3(q443) female gonads, the oocyte maturation rate is slow and prophase-arrested oocytes accumulate in the proximal gonad (pg) to the left of the spermatheca (sp). Few oocytes that have completed maturation and ovulation are observed in the uterus (ut; no oocytes are seen in A). (B) The maturation rate of young unmated itr-1(sy290gf) unc-24(e138); fog-3(q443) females is slow and their gonads resemble young unmated fog-3(q443) females. (C) In contrast to unmated itr-1(sy290gf) and control females, the maturation rate of young unmated unc-43(n498gf); fog-3(q443) females is high. Numerous oocytes that have recently completed maturation and ovulation are observed in the uterus (arrows). Scale bar: 20 µm.