Fig. 4. The Ubx
YPWM protein is a defective transcriptional repressor of
Dll and Antp. (A-F) In situ hybridization of mid-stage 11
embryos, hybridized with Dll (green) and Antp (red)
antisense probes. The broken white lines in A,C,E indicate the posterior
boundary of wg expression, which was detected in the same embryos
(not shown). Dll and Antp P1 transcripts shown in the
thoracic segments of (A,B) a wild type embryo, (C,D) an embryo ectopically
expressing wild type Ubx and (E,F) an embryo ectopically expressing
Ubx
YPWM protein. (G) A dose-response plot of Dll repression as
a function of the logarithm of the protein concentration of wild-type Ubx and
Ubx
YPWM.