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Fig. 5. vps33b knockdown disrupts biliary ultrastructure. (A,B) Electron micrographs of biliary epithelial cells from 5 dpf wild-type (A) and vps33b morpholino injected (B) larvae. The wild-type biliary cell cytoplasm has a homogeneous appearance. (B) A small bile duct comprising two bile duct cells from a vps33b morpholino-injected larva. Cytoplasm appears heterogeneously with multiple vesicles (black arrows). hep, hepatoctye; bd, bile duct lumen; bdc, bile duct cell.