Fig. 8. Altered localization of proteins in the cilial axoneme of Tg737^orpk mutants. On the wild-type choroid plexus, polycystin 1 (red) was localized predominantly at the base of the cilia (acetylated--tubulin, green), whereas, in the mutants, polycystin 1 accumulated in the bulb-like structures at the cilia tip. Scale bar: 20 µm.