Fig. 2. Morphological phenotypes resulting from the knockdown of genes important in neural crest development. Live zebrafish embryos at 40 hpf showing uninjected controls (A), and morpholino-induced knockdown phenotypes for foxd3 (B), sox10 (C) and foxd3+sox10 (D) genes. (B) foxd3 morphant animals had pigment, but a slightly smaller head than controls and a ventrally curled tail. (C) sox10 morphant animals had no pigment [as previously reported (see, Dutton et al., 2001b)], and occasionally a slight ventral curl to the tail. (D) foxd3+sox10 morphant animals had no pigment and a ventrally curled tail. Scale bar: A-D, 1 mm.