Fig. 8. Schematic of the developmental profile of sox10 and gnrh2 expression. (A) Dorsal view of the anterior neural plate at the 4- to 5-somite stage (12 hpf), depicting sox10 expression (purple) in the pre-migratory neural crest. (B) At 18-20 hpf, there are small populations of sox10-expressing cells on the backside of the forming optic cup (purple). (C) At 26 hpf, the perdurance of GFP allows the visualization of the cells previously expressing sox10 (green), which lie adjacent to gnrh2 cells (red) or co-express gnrh2 (yellow). (D) Within the developing midbrain at 48 hpf, the onset of sox10 expression (purple) is adjacent to but not overlapping with the gnrh2 expression (red).