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Fig. 7. Photoreceptor outer segments are tilted and clumped in pcdh15b morphants. Electron micrographs of day 4 (A-C) and day 7 (D-F) retinas of uninjected or 40 ng pcdh15b ATG Mo-injected larvae. The outer segments are slanted sideways and the nuclear layer is more condensed in morphants (B) in comparison to segments in uninjected larvae (A) or control 4 bp mismatch Mo-injected larvae (A'). In pcdh15b morphants, pigments cell melanosomes are rarely present between photoreceptor outer segments (B,D). The phenotype does not recover at day 7 and outer segments are often clustered together (D). (C,F) Higher magnification views of (B) and (E). Scale bar in F: 1 µm for A,B,D,E; 350 nm for C,F.