Fig. 7. Expression of nk2.2a and ntn1 is expanded dorsally in the
midbrain and hindbrain neural tube of mol-/- embryos, but
is reduced in smu-/- embryos. Lateral views of brains of
wild-type (A,D,G,J), mol-/- (B,E,H,K),
smu-/- (C,F,I,L) and
mol-/-;syu-/- double mutant (M,N)
embryos and mol-/- embryos treated with cyclopamine (O)
(cpm) analysed for expression of genes indicated bottom right. Arrows indicate
ectopic dorsal expression of ntn1 (B,E) and nk2.2a (H) in
mol-/- embryos. cpm, cyclopamine; e, endoderm; fp,
floorplate; MFP, medial floorplate.