Fig. 4. Wing phenotypes in mutant flies. (A) Wild type. Homozygous dally
mutant flies survive and sometimes (5%) display notches in the margin, which
are symptomatic of reduced Wingless signalling (B). Distal truncation of vein
5 is also frequent but we have not attempted to characterise this further. The
few homozygous dlp mutants that survive to adulthood (around 1%) have
wings characterised by two fully penetrant phenotypes: a narrowing of the
space between veins 3 and 4 (C), which suggests reduced hedgehog
signalling (Crozatier et al.,
2002) and (D) the formation of ectopic bristles on either side of
the margin (arrowheads, compare with wild type shown in E), an indication of
excess Wingless signalling. The same phenotypes are seen in surviving flies
carrying the mutation (dlpMH20 and
dallyMH32) over a large deficiency (Df(3L) ED4543
dlp and Df(3L) ED4413 dally, respectively).